Bayern Munich travel to a Hamburg side under new management still finding their way after changing tactics midway through their Champions League win over Manchester City.
Munich boss Pep Guardiola switched from a 3-4-1-2 system to a 4-1-2-3 in the middle of their victory over City, and the moved paid off as Bayern played one of their strongest matches of the season, culminating in Jerome Boateng's 90th-minute winner.
"We presented ourselves as a unit," said sports director Matthias Sammer.
Bayern chief executive Karl-Heinz Rummenigge added: "That was the best match we have played so far this season."
Guardiola would not reveal what system he would use against Hamburg. "We had problems controlling the ball, that's why we changed from a three-man backline to a four-man one," said Guardiola.
Missing from the City game was Franck Ribery, who will sit out the Hamburg contest as well.
"I don't know how long I will miss," said the Frenchman, who is dealing with a knee issue.
Last-placed Hamburg have their own issues, though they hope to have resolved some of them with the sacking of Mirko Slomka after one point and zero goals scored in three matches. The new man at the helm is former Hamburg under-23 team boss Josef Zinnbauer.
Things do not start too easily for Zinnbauer with Bayern, who he calls "the best team in the world". But Hamburg also have nothing to lose.
"The result is irrelevant. There is no other team who can dominate like Bayern. What is important to me is that we give a good account of ourselves and play as a unit," said Zinnbauer.
Leaders Bayer Leverkusen look to continue their roll away to VfL Wolfsburg, who have yet to win this season.
Leverkusen are the top-scoring team in the league with nine goals in three games - and they will be intent on bouncing back after a 1-0 Champions League loss in Monaco.
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